Department of Biology
Recent publications
Papers on C. elegans gonad development and collaborations
on C. elegans metabolism.
Koitz FA, Miller CP, Kinney B, Gordon KL. C. elegans pre-dauer starvation arrests germ cell proliferation and ligand presentation by the germline stem cell niche via a rapidly reversible, protein-based mechanism bioRxiv. https://doi.org/10.1101/2025.05.23.655783. In review at Development. UPDATED 11/2/2025

Li X, Gordon KL. (2025). MIG-21 regulates Wnt and Netrin signaling in gonad migration in C. elegans. PLOS Genetics 21(9): e1011866. https://doi.org/10.1371/journal.pgen.1011866

Kinney B, Menjivar-Hernandez J, Koitz F, Grinevich D, Baselios M, Hammell CM, Gordon KL. (2025). FLYWCH transcription factors act in a LIN-42/Period autoregulatory loop during gonad migration in C. elegans. bioRxiv. https://doi.org/10.1101/2025.07.10.664215. In revision at Genetics.

Ameyaa-Sakyi A, Harris TR, Clarke CE, David R. McMullin DR, Gordon KL, Sherwood DR, Hartman JH, Rand AA. (2025). Human mitochondrial CYP2E1-mediated styrene metabolism increases oxidative stress and impairs antioxidant rescue in Caenorhabditis elegans. Comparative Biochemistry and Physiology, Part C: Toxicology and Pharmacology. Volume 298, 110319. https://doi.org/10.1016/j.cbpc.2025.110319

Merritt RA, Heaney K, Shuchi N, Gordon KL*, Trammell SR*. (2025). Mid-IR Imaging Can Detect Waste Heat Production in the Nematode Caenorhabditis elegans. Journal of Biophotonics. https://doi.org/10.1002/jbio.202500078

Singh N*, Scott K*, Proctor J, Gordon KL. (2025). An RNAi screen of Rab GTPase genes in C. elegans reveals that morphogenesis has a higher demand than stem cell niche maintenance for rab-1 in the somatic cells of the reproductive system, G3 Genes|Genomes|Genetics, 2025; jkaf085, https://doi.org/10.1093/g3journal/jkaf085
(* indicates equally contributing authors)

Singh N, Zhang P, Li KJ, Gordon KL. (2024) The Rac pathway prevents cell fragmentation in a nonprotrusively migrating leader cell during C. elegans gonad organogenesis. Current Bio. doi: DOI: 10.1016/j.cub.2024.04.073

Gonzalez, HC, Misare KR, Mendenhall TT, Wolf BJ, Mulholland PJ, Gordon KL, Hartman JH. (2024) Transgenic expression of human cytochrome P450 2E1 in C. elegans and rat PC-12 cells sensitizes to ethanol-induced behavioral and mitochondrial effects. Biochem Biophys Res Commun. doi: 10.1016/j.bbrc.2024.150735

Gordon KL (2021). News &Views: Fatal decision made under pressure. Nat. Phys. https://doi.org/10.1038/s41567-021-01239-7

Gordon KL (2020). Recent advances in the genetic, anatomical, and environmental regulation of the C. elegans germ line progenitor zone.J. Dev. Biol. 2020, 8(3), 14; https://doi.org/10.3390/jdb8030014

Gordon KL, Zussman JW, Li X, Miller C, Sherwood DR. (2020). Stem cell niche exit in C. elegans via orientation and segregation of daughter cells by a cryptic cell outside the niche. eLife. DOI: 10.7554/eLife.56383.

Hartman, J, Smith L, Gordon K, Laranjeiro R, Driscoll M, Sherwood D, Meyer J. (2018). Swimming exercise and transient food deprivation in Caenorhabditis elegans promote mitochondrial maintenance and protect against chemical-induced mitotoxicity. Scientific Reports. 8(1): 8359. doi: 10.1038/s41598-018-26552-9

Evolution of gene regulation
Papers from Dr. Gordon's dissertation research.

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